A new target for cancer drugs
Suppressing cancer cells’ ability to cope with damage to their DNA could enhance dramatically the effectiveness of chemotherapy drugs such as cisplatin, according to a new pair of papers from MIT...
View ArticleTargeted nanoparticles show success in clinical trials
Targeted therapeutic nanoparticles that accumulate in tumors while bypassing healthy cells have shown promising results in an ongoing clinical trial, according to a new paper.The nanoparticles feature...
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New drug candidate shows promise against cancer
Drugs containing platinum are among the most powerful and widely used cancer drugs. However, such drugs have toxic side effects, and cancer cells can eventually become resistant to them. MIT chemistry...
View ArticleOn the hunt for rare cancer cells
Tumor cells circulating in a patient’s bloodstream can yield a great deal of information on how a tumor is responding to treatment and what drugs might be more effective against it. But first, these...
View ArticleHow to minimize the side effects of cancer treatment
New research from MIT may allow scientists to develop a test that can predict the severity of side effects of some common chemotherapy agents in individual patients, allowing doctors to tailor...
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Study reveals how melanoma evades chemotherapy
Nitric oxide (NO), a gas with many biological functions in healthy cells, can also help some cancer cells survive chemotherapy. A new study from MIT reveals one way in which this resistance may arise,...
View ArticleResistance is futile
Cisplatin is a chemotherapy drug given to more than half of all cancer patients. The drug kills cells very effectively by damaging nuclear DNA, but if tumors become resistant to cisplatin they often...
View ArticleBiologists ID new cancer weakness
About half of all cancer patients have a mutation in a gene called p53, which allows tumors to survive and continue growing even after chemotherapy severely damages their DNA. A new study from MIT...
View ArticleTargeting cancer with a triple threat
Delivering chemotherapy drugs in nanoparticle form could help reduce side effects by targeting the drugs directly to the tumors. In recent years, scientists have developed nanoparticles that deliver...
View ArticleFaculty highlight: Paula Hammond
As a chemical engineer, Paula Hammond began her career getting tiny polymers to transform when heated or stretched — by changing color, for example. But her passion turned to using those techniques to...
View ArticleAdvancing medicine, layer by layer
Personalized cancer treatments and better bone implants could grow from techniques demonstrated by graduate students Stephen W. Morton and Nisarg J. Shah, who are both working in chemical engineering...
View ArticleBetter chemotherapy through targeted delivery
Every year, about 100,000 Americans are diagnosed with brain tumors that have spread from elsewhere in the body. These tumors, known as metastases, are usually treated with surgery followed by...
View ArticleHow to identify drugs that work best for each patient
More than 100 drugs have been approved to treat cancer, but predicting which ones will help a particular patient is an inexact science at best.A new device developed at MIT may change that. The...
View ArticleReal-time data for cancer therapy
In the battle against cancer, which kills nearly 8 million people worldwide each year, doctors have in their arsenal many powerful weapons, including various forms of chemotherapy and radiation. What...
View ArticleM+Visión Fellow Carlos Castro named one of Spain’s top young innovators
Carlos Castro, a Catalyst Fellow in the Madrid–MIT M+Visión Consortium, was named one of the 2015 Innovators Under 35 Spain by MIT Technology Review, Spanish edition. Each year, 10 Spaniards under age...
View ArticleScientists sharpen the edges of cancer chemotherapy
Tackling unsolved problems is a cornerstone of scientific research, propelled by the power and promise of new technologies. Indeed, one of the shiniest tools in the biomedical toolkit these days is the...
View ArticleSensor could help doctors select effective cancer therapy
MIT chemical engineers have developed a new sensor that lets them see inside cancer cells and determine whether the cells are responding to a particular type of chemotherapy drug.The sensors, which...
View ArticleArtificial intelligence model “learns” from patient data to make cancer...
MIT researchers are employing novel machine-learning techniques to improve the quality of life for patients by reducing toxic chemotherapy and radiotherapy dosing for glioblastoma, the most aggressive...
View ArticleEvidence that gamma rhythm stimulation can treat neurological disorders is...
A surprising MIT study published in Nature at the end of 2016 helped to spur interest in the possibility that light flickering at the frequency of a particular gamma-band brain rhythm could produce...
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